Effects of Cremophor EL on distribution of Taxol to serum lipoproteins.

The clinical formulation of the anti-tumour agent Taxol involves the use of a mixture of ethanol and Cremophor EL. Gel electrophoresis and density-gradient ultracentrifugation were used to detect effects of Taxol infusions on serum lipoproteins. Use of the Cremophor vehicle results in a decrease in...

Full description

Bibliographic Details
Main Authors: Sykes, E., Woodburn, K., Decker, D., Kessel, D.
Format: Online
Language:English
Published: 1994
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033337/