Ultrastructural and Metabolic Determinants of Resistance to Azo-dye and Susceptibility to Nitrosamine Carcinogenesis of the Guinea-pig
During diethylnitrosamine (DEN) administration, a distinctive difference was observed between rats and guinea-pigs in the sequence of ultrastructural changes in the hepatic endoplasmic reticulum (ER). In DEN-induced hepatic tumour cells in the guinea-pig there was extensive proliferation of the roug...
Main Authors: | , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
1977
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025570/ |