Ultrastructural and Metabolic Determinants of Resistance to Azo-dye and Susceptibility to Nitrosamine Carcinogenesis of the Guinea-pig

During diethylnitrosamine (DEN) administration, a distinctive difference was observed between rats and guinea-pigs in the sequence of ultrastructural changes in the hepatic endoplasmic reticulum (ER). In DEN-induced hepatic tumour cells in the guinea-pig there was extensive proliferation of the roug...

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Bibliographic Details
Main Authors: Bryant, G. M., Sohal, R. S., Argus, M. F., Arcos, J. C.
Format: Online
Language:English
Published: 1977
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025570/