Effect of colchicine injection prior to the initiating phase of two-stage skin carcinogenesis in mice.

Colchicine injected 5, 9 and 24 h respectively before initiation (using s.c. injection of urethane for initiating action and TPA skin applications for promoting action, in female ICR mice) led to a significant increase in skin tumour incidence in the --9-h group, and an increase in percentage malign...

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Bibliographic Details
Main Authors: Berenblum, I., Armuth, V.
Format: Online
Language:English
Published: 1977
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025510/