Repeat-associated siRNAs cause chromatin silencing of retrotransposons in the Drosophila melanogaster germline

Silencing of genomic repeats, including transposable elements, in Drosophila melanogaster is mediated by repeat-associated short interfering RNAs (rasiRNAs) interacting with proteins of the Piwi subfamily. rasiRNA-based silencing is thought to be mechanistically distinct from both the RNA interferen...

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Bibliographic Details
Main Authors: Klenov, Mikhail S., Lavrov, Sergey A., Stolyarenko, Anastasia D., Ryazansky, Sergey S., Aravin, Alexei A., Tuschl, Thomas, Gvozdev, Vladimir A.
Format: Online
Language:English
Published: Oxford University Press 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2018648/