Filtering genes to improve sensitivity in oligonucleotide microarray data analysis

Many recent microarrays hold an enormous number of probe sets, thus raising many practical and theoretical problems in controlling the false discovery rate (FDR). Biologically, it is likely that most probe sets are associated with un-expressed genes, so the measured values are simply noise due to no...

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Bibliographic Details
Main Authors: Calza, Stefano, Raffelsberger, Wolfgang, Ploner, Alexander, Sahel, Jose, Leveillard, Thierry, Pawitan, Yudi
Format: Online
Language:English
Published: Oxford University Press 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2018638/