Cdc18/CDC6 activates the Rad3-dependent checkpoint in the fission yeast

A screen for genes that can ectopically activate a Rad3-dependent checkpoint block over mitosis in fission yeast has identified the DNA replication initiation factor cdc18 (known as CDC6 in other organisms). Either a stabilized form of Cdc18, the Cdc18-T6A phosphorylation mutant, or overexpression o...

Full description

Bibliographic Details
Main Authors: Fersht, Naomi, Hermand, Damien, Hayles, Jacqueline, Nurse, Paul
Format: Online
Language:English
Published: Oxford University Press 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2018612/