In vivo assessment of basic 2-nitroimidazole radiosensitizers.

The radiosensitizing efficiencies of 4 structural analogues of misonidazole (MISO) have been compared with that of the parent compound. Three of these were charged basic compounds, previously shown in vitro to be 10 times more efficient. Enhancement ratios were measured from pairs of tumour growth-d...

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Bibliographic Details
Main Authors: Williams, M. V., Denekamp, J., Minchinton, A. I., Stratford, M. R.
Format: Online
Language:English
Published: 1982
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2011061/