Different distribution of adriamycin in normal and leukaemic rats.

Adriamycin (ADR) accumulates in well-perfused organs in the rat. This effect is especially evident for long periods in marrow and spleen of healthy animals. In rats bearing the Brown Norway Acute Myeloid Leukaemia (BNML) the in vivo distribution is significantly different. Maximum ADR levels in thos...

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Bibliographic Details
Main Authors: Sonneveld, P., Van Bekkum, D. W.
Format: Online
Language:English
Published: 1981
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010630/