Antibody-induced changes in levels of cyclic adenosine monophosphate in leukaemic lymphocytes.

When L2C leukaemic B lymphocytes from guinea-pigs were incubated in vitro with antibody directed to their surface immunoglobulin (Ig), a rapid rise in intracellular adenosine 3':5'-phosphate (cyclic adenosine monophosphate, cAMP) was observed. Estimation of cAMP was by a protein-binding as...

Full description

Bibliographic Details
Main Authors: Virji, M., Stevenson, G. T.
Format: Online
Language:English
Published: 1979
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009930/