Monitoring salivary misonidazole in man: a possible alternative to plasma monitoring.

Concentrations of misonidazole and its O-demethylated metabolite Ro 05-9963 in the plasma and saliva of 10 patients with malignant disease have been determined. A good linear correlation was established between plasma and saliva misonidazole concentration, and salivary sampling was found to be suita...

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Bibliographic Details
Main Authors: Workman, P., Wiltshire, C. R., Plowman, P. N., Bleehen, N. M.
Format: Online
Language:English
Published: 1978
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009825/