The Response of a Mouse Sarcoma to Single and Divided Doses of X-rays and Fast Neutrons
The response of an experimental sarcoma to single doses and two fractions of x-rays and fast neutrons has been investigated to test the hypothesis that slowly shrinking sarcomata will reoxygenate poorly and therefore will benefit more from fractionated neutron treatment than from fractionated x-ray...
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| Format: | Online |
| Language: | English |
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1974
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009173/ |
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pubmed-2009173 |
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oai_dc |
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pubmed-20091732009-09-10 The Response of a Mouse Sarcoma to Single and Divided Doses of X-rays and Fast Neutrons Denekamp, J. Articles The response of an experimental sarcoma to single doses and two fractions of x-rays and fast neutrons has been investigated to test the hypothesis that slowly shrinking sarcomata will reoxygenate poorly and therefore will benefit more from fractionated neutron treatment than from fractionated x-ray treatment, in contrast with rapidly shrinking carcinomata. Neutrons were approximately three times more effective than x-rays, both for single doses and for two fractions given in 48 hours, when regrowth was used as a measure of response. This observation is closely similar to results previously obtained on a rat fibrosarcoma and contrasts with previous results from a mouse mammary carcinoma, and is in agreement with the hypothesis. 1974-04 /pmc/articles/PMC2009173/ /pubmed/4855057 Text en |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Denekamp, J. |
| spellingShingle |
Denekamp, J. The Response of a Mouse Sarcoma to Single and Divided Doses of X-rays and Fast Neutrons |
| author_facet |
Denekamp, J. |
| author_sort |
Denekamp, J. |
| title |
The Response of a Mouse Sarcoma to Single and Divided Doses of X-rays and Fast Neutrons |
| title_short |
The Response of a Mouse Sarcoma to Single and Divided Doses of X-rays and Fast Neutrons |
| title_full |
The Response of a Mouse Sarcoma to Single and Divided Doses of X-rays and Fast Neutrons |
| title_fullStr |
The Response of a Mouse Sarcoma to Single and Divided Doses of X-rays and Fast Neutrons |
| title_full_unstemmed |
The Response of a Mouse Sarcoma to Single and Divided Doses of X-rays and Fast Neutrons |
| title_sort |
response of a mouse sarcoma to single and divided doses of x-rays and fast neutrons |
| description |
The response of an experimental sarcoma to single doses and two fractions of x-rays and fast neutrons has been investigated to test the hypothesis that slowly shrinking sarcomata will reoxygenate poorly and therefore will benefit more from fractionated neutron treatment than from fractionated x-ray treatment, in contrast with rapidly shrinking carcinomata. Neutrons were approximately three times more effective than x-rays, both for single doses and for two fractions given in 48 hours, when regrowth was used as a measure of response. This observation is closely similar to results previously obtained on a rat fibrosarcoma and contrasts with previous results from a mouse mammary carcinoma, and is in agreement with the hypothesis. |
| publishDate |
1974 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009173/ |
| _version_ |
1611402939602042880 |