Interaction of bleomycin, hyperthermia and a calmodulin inhibitor (trifluoperazine) in mouse tumour cells: II. DNA damage, repair and chromatin changes.

We have reported in the preceding paper that the treatment of plateau phase mouse EMT6 tumour cells with a combination of hyperthermia (HT; 44 degrees C) and trifluoperazine (TFP; 30 micrograms ml-1; an inhibitor of calmodulin) greatly enhances the cytotoxicity of the antitumour drug belomycin (BLM)...

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Bibliographic Details
Main Authors: Smith, P. J., Mircheva, J., Bleehen, N. M.
Format: Online
Language:English
Published: 1986
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2001464/