Morphological and isoenzymatic differentiation of B-chronic lymphocytic leukaemia cells induced by phorbolester.
Fresh leukaemia cells from the peripheral blood of 6 patients with B-chronic lymphocytic leukaemia (CLL) were cultured in the continuous presence of the phorbolester 12-O-tetradecanoylphorbol 13-acetate (TPA) for in vitro induction of differentiation. Upon treatment with TPA the cells showed distinc...
Main Authors: | , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
1986
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2001325/ |