Haemoglobin C and S Role in Acquired Immunity against Plasmodium falciparum Malaria
A recently proposed mechanism of protection for haemoglobin C (HbC; β6Glu→Lys) links an abnormal display of PfEMP1, an antigen involved in malaria pathogenesis, on the surface of HbC infected erythrocytes together with the observation of reduced cytoadhesion of parasitized erythrocytes and impaired...
Main Authors: | , , , , , , , , , , , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Public Library of Science
2007
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1991593/ |