Response to mitoxantrone in advanced breast cancer: correlation with expression of c-erbB-2 protein and glutathione S-transferases.

Sixty-eight patients with advanced breast cancer were treated with mitoxantrone and clinical responses assessed. Expression of c-erbB-2 protein and cytosolic glutathione S-transferase (GST) isoenzymes pi, alpha and mu by the primary tumours of these patients was determined immunohistochemically, and...

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Bibliographic Details
Main Authors: Wright, C., Cairns, J., Cantwell, B. J., Cattan, A. R., Hall, A. G., Harris, A. L., Horne, C. H.
Format: Online
Language:English
Published: 1992
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977713/