The effect of ricin B chain on the intracellular trafficking of an A chain immunotoxin.
Covalent linkage of the A chain of ricin to the LICR-LOND-Fib75 monoclonal antibody produced an immunotoxin, Fib75-SS-ricin A, which demonstrated immunospecific toxicity to human bladder carcinoma cells in tissue culture (Forrester et al., 1984). The present studies have shown that ricin B chain pot...
| Main Authors: | , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
1991
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977687/ |