Human tumour-associated macrophages are capable of bone resorption.
Cellular mechanisms of bone resorption associated with skeletal metastasis are poorly understood. Human tumour-associated macrophages (TAMs) isolated from primary lung carcinomas were incubated on bone slices where they formed resorption lacunae after 14 days co-culture with a mouse marrow-derived s...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
1992
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977549/ |