Cis dichlorodiammine platinum induced DNA interstrand cross-links in primary cultures of human ovarian cancer.
We quantified and examined the kinetics of DNA interstrand cross links (DNA-ISC) caused by Cis dichlorodiammine platinum (DDP) using the method of alkaline elution in 58 highly purified human ovarian tumours growing in primary culture. A large heterogeneity in both the quantity and kinetics of DDP i...
Main Authors: | , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
1991
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977530/ |