Patterns of methylation of the c-myc gene in human colorectal cancer progression.

Over-expression and abnormal intracellular location of the product of the oncogene c-myc in colonic dysplasia and neoplasia may be related to alterations in epigenetic mechanisms controlling the functioning of this gene. We have investigated the methylation patterns of the c-myc oncogene in human co...

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Bibliographic Details
Main Authors: Sharrard, R. M., Royds, J. A., Rogers, S., Shorthouse, A. J.
Format: Online
Language:English
Published: 1992
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977397/