Effectiveness of isolated liver perfusion with mitomycin C in the treatment of liver tumours of rat colorectal cancer.

Dose limiting systemic toxicity prevents sufficient exploitation of the steep dose response relationship of most anticancer agents. In our rat liver tumour model (the CC531 colorectal carcinoma), isolated liver perfusion allows administration of higher doses of mitomycin C than hepatic artery infusi...

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Bibliographic Details
Main Authors: Marinelli, A., Dijkstra, F. R., van Dierendonck, J. H., Kuppen, P. J., Cornelisse, C. J., van de Velde, C. J.
Format: Online
Language:English
Published: 1991
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977309/