Geographical variations in the incidence of colorectal cancer in Britain.

The incidence of colorectal cancer was compared in nine towns in England and Wales, chosen to encompass a range of socio-economic conditions and spread of latitude in the country. Cases were ascertained through pathology records, supplemented by clinical notes. The pattern of variation in incidence...

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Main Authors: Barker, D. J., Godfrey, K. M.
Format: Online
Language:English
Published: 1984
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976979/
id pubmed-1976979
recordtype oai_dc
spelling pubmed-19769792009-09-10 Geographical variations in the incidence of colorectal cancer in Britain. Barker, D. J. Godfrey, K. M. Research Article The incidence of colorectal cancer was compared in nine towns in England and Wales, chosen to encompass a range of socio-economic conditions and spread of latitude in the country. Cases were ascertained through pathology records, supplemented by clinical notes. The pattern of variation in incidence was different for men and women. Among men incidences were highest in towns with better socio-economic conditions, whereas among women the trend was reversed. This supports the hypothesis that the dominant aetiological influences causing colorectal cancer differ in the two sexes. Mortality rates did not correlate closely with incidence. This, together with the markedly different patterns of incidence of colorectal cancer and appendicitis in the nine towns, casts doubt on the significance of a reported inverse correlation between regional mortality from colonic cancer and the consumption of pentosic fibre. 1984-11 /pmc/articles/PMC1976979/ /pubmed/6498068 Text en
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Barker, D. J.
Godfrey, K. M.
spellingShingle Barker, D. J.
Godfrey, K. M.
Geographical variations in the incidence of colorectal cancer in Britain.
author_facet Barker, D. J.
Godfrey, K. M.
author_sort Barker, D. J.
title Geographical variations in the incidence of colorectal cancer in Britain.
title_short Geographical variations in the incidence of colorectal cancer in Britain.
title_full Geographical variations in the incidence of colorectal cancer in Britain.
title_fullStr Geographical variations in the incidence of colorectal cancer in Britain.
title_full_unstemmed Geographical variations in the incidence of colorectal cancer in Britain.
title_sort geographical variations in the incidence of colorectal cancer in britain.
description The incidence of colorectal cancer was compared in nine towns in England and Wales, chosen to encompass a range of socio-economic conditions and spread of latitude in the country. Cases were ascertained through pathology records, supplemented by clinical notes. The pattern of variation in incidence was different for men and women. Among men incidences were highest in towns with better socio-economic conditions, whereas among women the trend was reversed. This supports the hypothesis that the dominant aetiological influences causing colorectal cancer differ in the two sexes. Mortality rates did not correlate closely with incidence. This, together with the markedly different patterns of incidence of colorectal cancer and appendicitis in the nine towns, casts doubt on the significance of a reported inverse correlation between regional mortality from colonic cancer and the consumption of pentosic fibre.
publishDate 1984
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976979/
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