Transforming growth factor beta 1 is implicated in the failure of tamoxifen therapy in human breast cancer.
Transforming growth factor-beta 1 (TGF-beta 1) is inhibitory for breast epithelial cells in vitro and treatment of breast cancer cell lines with tamoxifen results in a rise in TGF-beta 1 mRNA expression with associated inhibition of cell growth. To study whether these findings apply in vivo we exami...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
1991
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1972347/ |