The use of fluorescence in situ hybridisation combined with premature chromosome condensation for the identification of chromosome damage.

The technique of fusing mitotic cells to interphase cells, thereby producing condensation of the chromosomes of the interphase cell (so-called 'premature chromosome condensation' or PCC), has allowed detection of the initial number of chromosome breaks and their repair following ionising r...

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Bibliographic Details
Main Authors: Evans, J. W., Chang, J. A., Giaccia, A. J., Pinkel, D., Brown, J. M.
Format: Online
Language:English
Published: 1991
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1972339/