Enhancement of cyclophosphamide cytotoxicity in vivo by the benzamide analogue pyrazinamide.
The ability of pyrazinamide to enhance the in vivo cytotoxicity of cyclophosphamide in Lewis lung and RIF-1 tumours was investigated. Using an in vivo/in vitro excision assay a large single dose of pyrazinamide (500 mg kg-1 i.p.) was shown to enhance the tumour cell killing by cyclophosphamide. This...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
1994
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968828/ |