The identification of high and low risk groups for colorectal cancer using rectal mucosal crypt cell production rate (CCPR).

Rectal mucosal proliferation was measured in 116 individuals using the metaphase arrest technique crypt cell production rate (CCPR). CCPR was found to be significantly elevated in individuals with adenomas (n = 42, CCPR = 13 cc c-1h-1, range 7-25 Cl 10-15) compared with normals (n = 21, CCPR = 10 cc...

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Bibliographic Details
Main Authors: Rooney, P. S., Clarke, P. A., Gifford, K. A., Hardcastle, J. D., Armitage, N. C.
Format: Online
Language:English
Published: 1993
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968319/