Chemotherapeutic efficacy of the protein-doxorubicin conjugates on multidrug resistant rat hepatoma cell line in vitro.
In vitro studies were initiated to study the antitumour effect of protein-doxorubicin (DXR) conjugate on the growth of the multidrug resistant rat ascites hepatoma cell line, AH66DR. The 50% inhibitory concentration (IC50) for DXR in AH66DR cell line was 16 mumol l-1 (AH66 parental cell line, AH66P,...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
1993
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968189/ |