The identification of complete domains within protein sequences using accurate E-values for semi-global alignment

The sequencing of complete genomes has created a pressing need for automated annotation of gene function. Because domains are the basic units of protein function and evolution, a gene can be annotated from a domain database by aligning domains to the corresponding protein sequence. Ideally, complete...

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Bibliographic Details
Main Authors: Kann, Maricel G., Sheetlin, Sergey L., Park, Yonil, Bryant, Stephen H., Spouge, John L.
Format: Online
Language:English
Published: Oxford University Press 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950549/