Site-specific modification of Shigella flexneri virF mRNA by tRNA-guanine transglycosylase in vitro

Shigella flexneri is an enteropathogen responsible for severe dysentery in humans. VirF is a key transcriptional regulator that activates the expression of the downstream virulence factors required for cellular invasion and cell-to-cell spread of this pathogen. There are several environmental factor...

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Bibliographic Details
Main Authors: Hurt, Julie K., Olgen, Sureyya, Garcia, George A.
Format: Online
Language:English
Published: Oxford University Press 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950534/