Phosphoinositide-dependent protein kinase-1 (PDK1)-independent activation of the protein kinase C substrate, protein kinase D
Phosphoinoisitide dependent kinase l (PDK1) is proposed to phosphorylate a key threonine residue within the catalytic domain of the protein kinase C (PKC) superfamily that controls the stability and catalytic competence of these kinases. Hence, in PDK1-null embryonic stem cells intracellular levels...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Elsevier Science B.V
2007
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1942071/ |