TCRζdimlymphocytes define populations of circulating effector cells that migrate to inflamed tissues
The T-cell receptor ζ (TCRζ) chain is a master sensor and regulator of lymphocyte responses. Loss of TCRζ expression has been documented in infectious, inflammatory, and malignant diseases, suggesting that it may serve to limit T-cell reactivity and effector responses at sites of tissue damage. Thes...
Main Authors: | , , , , , , , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
American Society of Hematology
2007
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1939810/ |