Transbilayer Phospholipid Movements in ABCA1-Deficient Cells

Tangier disease is an inherited disorder that results in a deficiency in circulating levels of HDL. Although the disease is known to be caused by mutations in the ABCA1 gene, the mechanism by which lesions in the ABCA1 ATPase effect this outcome is not known. The inability of ABCA1 knockout mice (AB...

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Bibliographic Details
Main Authors: Williamson, Patrick, Halleck, Margaret S., Malowitz, Jonathan, Ng, Susan, Fan, Xiaoxuan, Krahling, Stephen, Remaley, Alan T., Schlegel, Robert A.
Format: Online
Language:English
Published: Public Library of Science 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1939730/