Molecular Basis of Resistance to Muramidase and Cationic Antimicrobial Peptide Activity of Lysozyme in Staphylococci

It has been shown recently that modification of peptidoglycan by O-acetylation renders pathogenic staphylococci resistant to the muramidase activity of lysozyme. Here, we show that a Staphylococcus aureus double mutant defective in O-acetyltransferase A (OatA), and the glycopeptide resistance-associ...

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Bibliographic Details
Main Authors: Herbert, Silvia, Bera, Agnieszka, Nerz, Christiane, Kraus, Dirk, Peschel, Andreas, Goerke, Christiane, Meehl, Michael, Cheung, Ambrose, Götz, Friedrich
Format: Online
Language:English
Published: Public Library of Science 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1933452/