Pcons.net: protein structure prediction meta server

The Pcons.net Meta Server (http://pcons.net) provides improved automated tools for protein structure prediction and analysis using consensus. It essentially implements all the steps necessary to produce a high quality model of a protein. The whole process is fully automated and a potential user only...

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Main Authors: Wallner, Björn, Larsson, Per, Elofsson, Arne
Format: Online
Language:English
Published: Oxford University Press 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1933226/
id pubmed-1933226
recordtype oai_dc
spelling pubmed-19332262007-07-31 Pcons.net: protein structure prediction meta server Wallner, Björn Larsson, Per Elofsson, Arne Articles The Pcons.net Meta Server (http://pcons.net) provides improved automated tools for protein structure prediction and analysis using consensus. It essentially implements all the steps necessary to produce a high quality model of a protein. The whole process is fully automated and a potential user only submits the protein sequence. For PSI-BLAST detectable targets, an accurate model is generated within minutes of submission. For more difficult targets the sequence is automatically submitted to publicly available fold-recognition servers that use more advanced approaches to find distant structural homologs. The results from these servers are analyzed and assessed for structural correctness using Pcons and ProQ; and the user is presented with a ranked list of possible models. In addition, if the protein sequence contains more than one domain, these are automatically parsed out and resubmitted to the server as individual queries. Oxford University Press 2007-07 2007-06-21 /pmc/articles/PMC1933226/ /pubmed/17584798 http://dx.doi.org/10.1093/nar/gkm319 Text en © 2007 The Author(s) http://creativecommons.org/licenses/by-nc/2.0/uk/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Wallner, Björn
Larsson, Per
Elofsson, Arne
spellingShingle Wallner, Björn
Larsson, Per
Elofsson, Arne
Pcons.net: protein structure prediction meta server
author_facet Wallner, Björn
Larsson, Per
Elofsson, Arne
author_sort Wallner, Björn
title Pcons.net: protein structure prediction meta server
title_short Pcons.net: protein structure prediction meta server
title_full Pcons.net: protein structure prediction meta server
title_fullStr Pcons.net: protein structure prediction meta server
title_full_unstemmed Pcons.net: protein structure prediction meta server
title_sort pcons.net: protein structure prediction meta server
description The Pcons.net Meta Server (http://pcons.net) provides improved automated tools for protein structure prediction and analysis using consensus. It essentially implements all the steps necessary to produce a high quality model of a protein. The whole process is fully automated and a potential user only submits the protein sequence. For PSI-BLAST detectable targets, an accurate model is generated within minutes of submission. For more difficult targets the sequence is automatically submitted to publicly available fold-recognition servers that use more advanced approaches to find distant structural homologs. The results from these servers are analyzed and assessed for structural correctness using Pcons and ProQ; and the user is presented with a ranked list of possible models. In addition, if the protein sequence contains more than one domain, these are automatically parsed out and resubmitted to the server as individual queries.
publisher Oxford University Press
publishDate 2007
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1933226/
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