eProbalign: generation and manipulation of multiple sequence alignments using partition function posterior probabilities

Probalign computes maximal expected accuracy multiple sequence alignments from partition function posterior probabilities. To date, Probalign is among the very best scoring methods on the BAliBASE, HOMSTRAD and OXBENCH benchmarks. Here, we introduce eProbalign, which is an online implementation of t...

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Main Authors: Chikkagoudar, Satish, Roshan, Usman, Livesay, Dennis
Format: Online
Language:English
Published: Oxford University Press 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1933135/
id pubmed-1933135
recordtype oai_dc
spelling pubmed-19331352007-07-31 eProbalign: generation and manipulation of multiple sequence alignments using partition function posterior probabilities Chikkagoudar, Satish Roshan, Usman Livesay, Dennis Articles Probalign computes maximal expected accuracy multiple sequence alignments from partition function posterior probabilities. To date, Probalign is among the very best scoring methods on the BAliBASE, HOMSTRAD and OXBENCH benchmarks. Here, we introduce eProbalign, which is an online implementation of the approach. Moreover, the eProbalign web server doubles as an online platform for post-alignment analysis. The heart-and-soul of the post-alignment functionality is the Probalign Alignment Viewer applet, which provides users a convenient means to manipulate the alignments by posterior probabilities. The viewer can also be used to produce graphical and text versions of the output. The eProbalign web server and underlying Probalign source code is freely accessible at http://probalign.njit.edu Oxford University Press 2007-07 2007-05-07 /pmc/articles/PMC1933135/ /pubmed/17485479 http://dx.doi.org/10.1093/nar/gkm267 Text en © 2007 The Author(s) http://creativecommons.org/licenses/by-nc/2.0/uk/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Chikkagoudar, Satish
Roshan, Usman
Livesay, Dennis
spellingShingle Chikkagoudar, Satish
Roshan, Usman
Livesay, Dennis
eProbalign: generation and manipulation of multiple sequence alignments using partition function posterior probabilities
author_facet Chikkagoudar, Satish
Roshan, Usman
Livesay, Dennis
author_sort Chikkagoudar, Satish
title eProbalign: generation and manipulation of multiple sequence alignments using partition function posterior probabilities
title_short eProbalign: generation and manipulation of multiple sequence alignments using partition function posterior probabilities
title_full eProbalign: generation and manipulation of multiple sequence alignments using partition function posterior probabilities
title_fullStr eProbalign: generation and manipulation of multiple sequence alignments using partition function posterior probabilities
title_full_unstemmed eProbalign: generation and manipulation of multiple sequence alignments using partition function posterior probabilities
title_sort eprobalign: generation and manipulation of multiple sequence alignments using partition function posterior probabilities
description Probalign computes maximal expected accuracy multiple sequence alignments from partition function posterior probabilities. To date, Probalign is among the very best scoring methods on the BAliBASE, HOMSTRAD and OXBENCH benchmarks. Here, we introduce eProbalign, which is an online implementation of the approach. Moreover, the eProbalign web server doubles as an online platform for post-alignment analysis. The heart-and-soul of the post-alignment functionality is the Probalign Alignment Viewer applet, which provides users a convenient means to manipulate the alignments by posterior probabilities. The viewer can also be used to produce graphical and text versions of the output. The eProbalign web server and underlying Probalign source code is freely accessible at http://probalign.njit.edu
publisher Oxford University Press
publishDate 2007
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1933135/
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