eProbalign: generation and manipulation of multiple sequence alignments using partition function posterior probabilities
Probalign computes maximal expected accuracy multiple sequence alignments from partition function posterior probabilities. To date, Probalign is among the very best scoring methods on the BAliBASE, HOMSTRAD and OXBENCH benchmarks. Here, we introduce eProbalign, which is an online implementation of t...
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Oxford University Press
2007
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1933135/ |
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pubmed-19331352007-07-31 eProbalign: generation and manipulation of multiple sequence alignments using partition function posterior probabilities Chikkagoudar, Satish Roshan, Usman Livesay, Dennis Articles Probalign computes maximal expected accuracy multiple sequence alignments from partition function posterior probabilities. To date, Probalign is among the very best scoring methods on the BAliBASE, HOMSTRAD and OXBENCH benchmarks. Here, we introduce eProbalign, which is an online implementation of the approach. Moreover, the eProbalign web server doubles as an online platform for post-alignment analysis. The heart-and-soul of the post-alignment functionality is the Probalign Alignment Viewer applet, which provides users a convenient means to manipulate the alignments by posterior probabilities. The viewer can also be used to produce graphical and text versions of the output. The eProbalign web server and underlying Probalign source code is freely accessible at http://probalign.njit.edu Oxford University Press 2007-07 2007-05-07 /pmc/articles/PMC1933135/ /pubmed/17485479 http://dx.doi.org/10.1093/nar/gkm267 Text en © 2007 The Author(s) http://creativecommons.org/licenses/by-nc/2.0/uk/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
repository_type |
Open Access Journal |
institution_category |
Foreign Institution |
institution |
US National Center for Biotechnology Information |
building |
NCBI PubMed |
collection |
Online Access |
language |
English |
format |
Online |
author |
Chikkagoudar, Satish Roshan, Usman Livesay, Dennis |
spellingShingle |
Chikkagoudar, Satish Roshan, Usman Livesay, Dennis eProbalign: generation and manipulation of multiple sequence alignments using partition function posterior probabilities |
author_facet |
Chikkagoudar, Satish Roshan, Usman Livesay, Dennis |
author_sort |
Chikkagoudar, Satish |
title |
eProbalign: generation and manipulation of multiple sequence alignments using partition function posterior probabilities |
title_short |
eProbalign: generation and manipulation of multiple sequence alignments using partition function posterior probabilities |
title_full |
eProbalign: generation and manipulation of multiple sequence alignments using partition function posterior probabilities |
title_fullStr |
eProbalign: generation and manipulation of multiple sequence alignments using partition function posterior probabilities |
title_full_unstemmed |
eProbalign: generation and manipulation of multiple sequence alignments using partition function posterior probabilities |
title_sort |
eprobalign: generation and manipulation of multiple sequence alignments using partition function posterior probabilities |
description |
Probalign computes maximal expected accuracy multiple sequence alignments from partition function posterior probabilities. To date, Probalign is among the very best scoring methods on the BAliBASE, HOMSTRAD and OXBENCH benchmarks. Here, we introduce eProbalign, which is an online implementation of the approach. Moreover, the eProbalign web server doubles as an online platform for post-alignment analysis. The heart-and-soul of the post-alignment functionality is the Probalign Alignment Viewer applet, which provides users a convenient means to manipulate the alignments by posterior probabilities. The viewer can also be used to produce graphical and text versions of the output. The eProbalign web server and underlying Probalign source code is freely accessible at http://probalign.njit.edu |
publisher |
Oxford University Press |
publishDate |
2007 |
url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1933135/ |
_version_ |
1611398551492886528 |