Population Bottlenecks as a Potential Major Shaping Force of Human Genome Architecture

Population Bottlenecks as a Potential Major Shaping Force of Human Genome Architecture

The modern synthetic view of human evolution proposes that the fixation of novel mutations is driven by the balance among selective advantage, selective disadvantage, and genetic drift. When considering the global architecture of the human genome, the same model can be applied to understanding the r...

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Bibliographic Details
Main Authors: Gherman, Adrian, Chen, Peter E, Teslovich, Tanya M, Stankiewicz, Pawel, Withers, Marjorie, Kashuk, Carl S, Chakravarti, Aravinda, Lupski, James R, Cutler, David J, Katsanis, Nicholas
Format: Online
Language:English
Published: Public Library of Science 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1925129/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1925129/

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