Early Energy Deficit in Huntington Disease: Identification of a Plasma Biomarker Traceable during Disease Progression

Huntington disease (HD) is a fatal neurodegenerative disorder, with no effective treatment. The pathogenic mechanisms underlying HD have not been elucidated, but weight loss, associated with chorea and cognitive decline, is a characteristic feature of the disease that is accessible to investigation....

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Main Authors: Mochel, Fanny, Charles, Perrine, Seguin, François, Barritault, Julie, Coussieu, Christiane, Perin, Laurence, Le Bouc, Yves, Gervais, Christiane, Carcelain, Guislaine, Vassault, Anne, Feingold, Josué, Rabier, Daniel, Durr, Alexandra
Format: Online
Language:English
Published: Public Library of Science 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1919424/