Transcriptional Regulation of Multi-Drug Tolerance and Antibiotic-Induced Responses by the Histone-Like Protein Lsr2 in M. tuberculosis

Multi-drug tolerance is a key phenotypic property that complicates the sterilization of mammals infected with Mycobacterium tuberculosis. Previous studies have established that iniBAC, an operon that confers multi-drug tolerance to M. bovis BCG through an associated pump-like activity, is induced by...

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Bibliographic Details
Main Authors: Colangeli, Roberto, Helb, Danica, Vilchèze, Catherine, Hazbón, Manzour Hernando, Lee, Chee-Gun, Safi, Hassan, Sayers, Brendan, Sardone, Irene, Jones, Marcus B, Fleischmann, Robert D, Peterson, Scott N, Jacobs, William R, Alland, David
Format: Online
Language:English
Published: Public Library of Science 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1894825/