The opposing homeobox genes Goosecoid and Vent1/2 self-regulate Xenopus patterning

We present a loss-of-function study using antisense morpholino (MO) reagents for the organizer-specific gene Goosecoid (Gsc) and the ventral genes Vent1 and Vent2. Unlike in the mouse Gsc is required in Xenopus for mesodermal patterning during gastrulation, causing phenotypes ranging from reduction...

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Bibliographic Details
Main Authors: Sander, Veronika, Reversade, Bruno, De Robertis, E M
Format: Online
Language:English
Published: Nature Publishing Group 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1894760/