Modeling Systems-Level Regulation of Host Immune Responses

Many pathogens are able to manipulate the signaling pathways responsible for the generation of host immune responses. Here we examine and model a respiratory infection system in which disruption of host immune functions or of bacterial factors changes the dynamics of the infection. We synthesize the...

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Bibliographic Details
Main Authors: Thakar, Juilee, Pilione, Mylisa, Kirimanjeswara, Girish, Harvill, Eric T, Albert, Réka
Format: Online
Language:English
Published: Public Library of Science 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892604/