Selection for Robustness in Mutagenized RNA Viruses
Mutational robustness is defined as the constancy of a phenotype in the face of deleterious mutations. Whether robustness can be directly favored by natural selection remains controversial. Theory and in silico experiments predict that, at high mutation rates, slow-replicating genotypes can potentia...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
Public Library of Science
2007
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892351/ |