Thioredoxin Glutathione Reductase from Schistosoma mansoni: An Essential Parasite Enzyme and a Key Drug Target

Thioredoxin Glutathione Reductase from Schistosoma mansoni: An Essential Parasite Enzyme and a Key Drug Target

Using both genetic and biochemical approaches, David Williams and colleagues show that the parasite thioredoxin glutathione reductase meets all the major criteria to be a key target for antischistosomal chemotherapy.

Bibliographic Details
Main Authors: Kuntz, Angela N, Davioud-Charvet, Elisabeth, Sayed, Ahmed A, Califf, Lindsay L, Dessolin, Jean, Arnér, Elias S. J, Williams, David L
Format: Online
Language:English
Published: Public Library of Science 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892040/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892040/

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