The Flagellum of Pseudomonas aeruginosa Is Required for Resistance to Clearance by Surfactant Protein A

Surfactant protein A (SP-A) is an important lung innate immune protein that kills microbial pathogens by opsonization and membrane permeabilization. We investigated the basis of SP-A-mediated pulmonary clearance of Pseudomonas aeruginosa using genetically-engineered SP-A mice and a library of signat...

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Bibliographic Details
Main Authors: Zhang, Shiping, McCormack, Francis X., Levesque, Roger C., O'Toole, George A., Lau, Gee W.
Format: Online
Language:English
Published: Public Library of Science 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1891440/