TNM staging of foregut (neuro)endocrine tumors: a consensus proposal including a grading system

The need for standards in the management of patients with endocrine tumors of the digestive system prompted the European Neuroendocrine Tumor Society (ENETS) to organize a first Consensus Conference, which was held in Frascati (Rome) and was based on the recently published ENETS guidelines on the di...

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Main Authors: Rindi, G., Klöppel, G., Alhman, H., Caplin, M., Couvelard, A., de Herder, W. W., Erikssson, B., Falchetti, A., Falconi, M., Komminoth, P., Körner, M., Lopes, J. M., McNicol, A-M., Nilsson, O., Perren, A., Scarpa, A., Scoazec, J-Y., Wiedenmann, B.
Format: Online
Language:English
Published: Springer-Verlag 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1888719/
id pubmed-1888719
recordtype oai_dc
spelling pubmed-18887192007-06-08 TNM staging of foregut (neuro)endocrine tumors: a consensus proposal including a grading system Rindi, G. Klöppel, G. Alhman, H. Caplin, M. Couvelard, A. de Herder, W. W. Erikssson, B. Falchetti, A. Falconi, M. Komminoth, P. Körner, M. Lopes, J. M. McNicol, A-M. Nilsson, O. Perren, A. Scarpa, A. Scoazec, J-Y. Wiedenmann, B. Original Article The need for standards in the management of patients with endocrine tumors of the digestive system prompted the European Neuroendocrine Tumor Society (ENETS) to organize a first Consensus Conference, which was held in Frascati (Rome) and was based on the recently published ENETS guidelines on the diagnosis and treatment of digestive neuroendocrine tumors (NET). Here, we report the tumor–node–metastasis proposal for foregut NETs of the stomach, duodenum, and pancreas that was designed, discussed, and consensually approved at this conference. In addition, we report the proposal for a working formulation for the grading of digestive NETs based on mitotic count and Ki-67 index. This proposal, which needs to be validated, is meant to help clinicians in the stratification, treatment, and follow-up of patients. Springer-Verlag 2006-09-12 2006-10 /pmc/articles/PMC1888719/ /pubmed/16967267 http://dx.doi.org/10.1007/s00428-006-0250-1 Text en © Springer-Verlag 2006
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Rindi, G.
Klöppel, G.
Alhman, H.
Caplin, M.
Couvelard, A.
de Herder, W. W.
Erikssson, B.
Falchetti, A.
Falconi, M.
Komminoth, P.
Körner, M.
Lopes, J. M.
McNicol, A-M.
Nilsson, O.
Perren, A.
Scarpa, A.
Scoazec, J-Y.
Wiedenmann, B.
spellingShingle Rindi, G.
Klöppel, G.
Alhman, H.
Caplin, M.
Couvelard, A.
de Herder, W. W.
Erikssson, B.
Falchetti, A.
Falconi, M.
Komminoth, P.
Körner, M.
Lopes, J. M.
McNicol, A-M.
Nilsson, O.
Perren, A.
Scarpa, A.
Scoazec, J-Y.
Wiedenmann, B.
TNM staging of foregut (neuro)endocrine tumors: a consensus proposal including a grading system
author_facet Rindi, G.
Klöppel, G.
Alhman, H.
Caplin, M.
Couvelard, A.
de Herder, W. W.
Erikssson, B.
Falchetti, A.
Falconi, M.
Komminoth, P.
Körner, M.
Lopes, J. M.
McNicol, A-M.
Nilsson, O.
Perren, A.
Scarpa, A.
Scoazec, J-Y.
Wiedenmann, B.
author_sort Rindi, G.
title TNM staging of foregut (neuro)endocrine tumors: a consensus proposal including a grading system
title_short TNM staging of foregut (neuro)endocrine tumors: a consensus proposal including a grading system
title_full TNM staging of foregut (neuro)endocrine tumors: a consensus proposal including a grading system
title_fullStr TNM staging of foregut (neuro)endocrine tumors: a consensus proposal including a grading system
title_full_unstemmed TNM staging of foregut (neuro)endocrine tumors: a consensus proposal including a grading system
title_sort tnm staging of foregut (neuro)endocrine tumors: a consensus proposal including a grading system
description The need for standards in the management of patients with endocrine tumors of the digestive system prompted the European Neuroendocrine Tumor Society (ENETS) to organize a first Consensus Conference, which was held in Frascati (Rome) and was based on the recently published ENETS guidelines on the diagnosis and treatment of digestive neuroendocrine tumors (NET). Here, we report the tumor–node–metastasis proposal for foregut NETs of the stomach, duodenum, and pancreas that was designed, discussed, and consensually approved at this conference. In addition, we report the proposal for a working formulation for the grading of digestive NETs based on mitotic count and Ki-67 index. This proposal, which needs to be validated, is meant to help clinicians in the stratification, treatment, and follow-up of patients.
publisher Springer-Verlag
publishDate 2006
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1888719/
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