The Dynamics of Signal Triggering in a gp130-Receptor Complex

gp130 is a shared signal-transducing membrane-associated receptor for several hematopoietic cytokines. The 30 Å resolution cryo-electron microscopy (cryo-EM) structure of the Interleukin 11(IL-11)-IL-11 Receptor-gp130 extracellular complex reveals the architecture and dynamics of this gp130-containi...

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Bibliographic Details
Main Authors: Matadeen, Rishi, Hon, Wai-Ching, Heath, John K., Jones, E. Yvonne, Fuller, Stephen
Format: Online
Language:English
Published: Cell Press 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885967/