WIP Regulates the Stability and Localization of WASP to Podosomes in Migrating Dendritic Cells

WIP Regulates the Stability and Localization of WASP to Podosomes in Migrating Dendritic Cells

The Wiskott-Aldrich Syndrome protein (WASP) is an adaptor protein that is essential for podosome formation in hematopoietic cells [1]. Given that 80% of identified Wiskott-Aldrich Syndrome patients result from mutations in the binding site for WASP-interacting-protein (WIP) [2], we examined the poss...

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Main Authors: Chou, Hsiu-Chuan, Antón, Inés M., Holt, Mark R., Curcio, Claudia, Lanzardo, Stefania, Worth, Austen, Burns, Siobhan, Thrasher, Adrian J., Jones, Gareth E., Calle, Yolanda
Format: Online
Language:English
Published: Cell Press 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885947/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885947/

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