Accumulation of Pathological Prion Protein PrPSc in the Skin of Animals with Experimental and Natural Scrapie

Prion infectivity and its molecular marker, the pathological prion protein PrPSc, accumulate in the central nervous system and often also in lymphoid tissue of animals or humans affected by transmissible spongiform encephalopathies. Recently, PrPSc was found in tissues previously considered not to b...

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Bibliographic Details
Main Authors: Thomzig, Achim, Schulz-Schaeffer, Walter, Wrede, Arne, Wemheuer, Wilhelm, Brenig, Bertram, Kratzel, Christine, Lemmer, Karin, Beekes, Michael
Format: Online
Language:English
Published: Public Library of Science 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1876502/