Stem Cell Fate Analysis Revisited: Interpretation of Individual Clone Dynamics in the Light of a New Paradigm of Stem Cell Organization

Many experimental findings on heterogeneity, flexibility, and plasticity of tissue stem cells are currently challenging stem cell concepts that assume a cell intrinsically predefined, unidirectional differentiation program. In contrast to these classical concepts, nonhierarchical self-organizing sys...

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Bibliographic Details
Main Authors: Roeder, Ingo, Braesel, Katrin, Lorenz, Ronny, Loeffler, Markus
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1874676/