Stem Cell Fate Analysis Revisited: Interpretation of Individual Clone Dynamics in the Light of a New Paradigm of Stem Cell Organization
Many experimental findings on heterogeneity, flexibility, and plasticity of tissue stem cells are currently challenging stem cell concepts that assume a cell intrinsically predefined, unidirectional differentiation program. In contrast to these classical concepts, nonhierarchical self-organizing sys...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
Hindawi Publishing Corporation
2007
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1874676/ |