Distance constraints between microRNA target sites dictate efficacy and cooperativity
MicroRNAs (miRNAs) have the potential to regulate the expression of thousands of genes, but the mechanisms that determine whether a gene is targeted or not are poorly understood. We studied the genomic distribution of distances between pairs of identical miRNA seeds and found a propensity for modera...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
Oxford University Press
2007
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1874663/ |