Whole-Genome Sequencing and Assembly with High-Throughput, Short-Read Technologies

While recently developed short-read sequencing technologies may dramatically reduce the sequencing cost and eventually achieve the $1000 goal for re-sequencing, their limitations prevent the de novo sequencing of eukaryotic genomes with the standard shotgun sequencing protocol. We present SHRAP (SHo...

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Bibliographic Details
Main Authors: Sundquist, Andreas, Ronaghi, Mostafa, Tang, Haixu, Pevzner, Pavel, Batzoglou, Serafim
Format: Online
Language:English
Published: Public Library of Science 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1871613/