Analysis of alcohol dependence phenotype in the COGA families using covariates to detect linkage

Linkage analysis methods that incorporate etiological heterogeneity of complex diseases are likely to demonstrate greater power than traditional linkage analysis methods. Several such methods use covariates to discriminate between linked and unlinked pedigrees with respect to a certain disease locus...

Full description

Bibliographic Details
Main Authors: Reck, Brian H, Mukhopadhyay, Nandita, Tsai, Hui-Ju, Weeks, Daniel E
Format: Online
Language:English
Published: BioMed Central 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866792/